Health Care

Metastatic Breast Cancer cured in Future

Metastatic Breast Cancer cured in Future

Asparagine, an amino acid also found in dairy and poultry, somehow helps cancerous cells to move from the breast into the bloodstream and colonise other areas of the body, Cambridge researchers found.

The study, reported in the journal Nature, was carried out on mice which had a highly developed breast cancer.

"These exciting findings provide the foundation for research into an entirely new type of cancer treatment that targets the metabolism of tumour cells to control their growth and spread". Albeit cure propositions late-stage breast cancer is segmented into the three extensive categories of chemotherapy, radiation therapy and surgery, their petition is habitually varied than in earlier stages.

Normally they would die in a couple of weeks as the tumour spread throughout the body. Some of these mice were then fed on a diet low on asparagines.

In treating the mice, the researchers found that restricting the amount of asparagus in the animals' diet reduced the spread of the cancer.

Could an asparagine-restricted diet help stop tumour spread in cancer patients? Professor Hannon said that their studies show that some cancers are "addicted" to some amino acids or parts of our diets specifically.

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"This is interesting research looking at how cutting off the supply of nutrients essential to cancer's spread could help restrain tumours". One of the authors, Simon Knott of Cedars-Sinai Hospital in Los Angeles, noted that the study adds credence to the theory that there is a complex interplay between diet and cancer.

Greg Hannon, from Cancer Research UK's Cambridge Institute, said that they became interested in asparagine because they had noticed that breast cancer patients with the greatest propensity to...

Death from cancers is usually due to the spread of the cancer to other major organs or metastasis of the cancer to lungs, brain, bones, liver etc. Reducing the asparagines did not affect the main tumor in any way but stopped the cancer from spreading. This drug is being used routinely to treat acute lymphoblastic leukaemia.

"Further studies are needed to confirm whether this would have the same impact in patients".

Whole grains such as wheat, rye, oats, rice, corn, bulgur and barley, along with green leafy vegetables, such as lettuce, spinach, swiss chard, endives, beet greens and romaine, as well as fruit are known to contain phytochemicals with antioxidant, antiestrogen and chemopreventive properties that may prevent cancer.


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